News
- Gunmen kill more than 160 people in attacks on two west Nigeria villages [The Guardian World]
US News
- Trump is honoring these Black icons in quest "to restore the Nation" [Axios]
- U.S.-Iran nuclear talks back on after Arab leaders lobby White House [Axios]
- Exclusive: 300+ ex-DOJ lawyers demand transparent Minnesota shooting probes [Axios]
- The economy is the world's most important problem, but not America's [Axios]
- Trump's 2020 grievances fuel election power grabs [Axios]
- Trump administration pulling 700 immigration agents from Minnesota [Axios]
- Death of New START heralds "a world with more nuclear risk" [Axios]
- Exclusive: Majority of Trump voters back solar power, poll finds [Axios]
Tech
- Workday reveals around 400 staff soon won't have to work another day [The Register]
- From guardrails to governance: A CEO’s guide for securing agentic systems [MIT Technology Review]
- The Download: the future of nuclear power plants, and social media-fueled AI hype [MIT Technology Review]
Business
- Anthropic is going after ChatGPT in a buzzy new ad campaign [Quartz]
- Can emerging markets’ stellar run continue? [The Economist]
- Impulse spending is stopping you from living your best life. Here’s how to fix it [Quartz]
- AI meets ICE [Quartz]
- The weight loss drug giants are going in opposite directions [Quartz]
- The jobs market is stuck in place to start the year [Quartz]
- Starbucks says human connection is driving a comeback. Baristas say it’s breaking them [Quartz]
- Six Flags introduces regional park access, letting pass holders access more than one park [Quartz]
- NASA won't be sending astronauts to the moon this month [Quartz]
- The 5 most romantic states in America — and the 5 least romantic [Quartz]
- The best used cars to buy right now, according to Consumer Reports [Quartz]
Science
- Remote region in Greece has one of the most genetically distinct populations in Europe [Live Science]
- Nasal spray could prevent infections from any flu strain [New Scientist]
- Sebastião Salgado's stunning shots of the world's icy regions [New Scientist]
- Unexpectedly moving book makes the case for the Arctic [New Scientist]
- Holy prosociality! Batman makes people stand for pregnant passengers [New Scientist]
- Why Elon Musk has misunderstood the point of Star Trek [New Scientist]
- A new 'brief history' of the universe paints a wide picture [New Scientist]
- New Scientist recommends 28 Years Later: The Bone Temple [New Scientist]
- The Beauty may be horror TV but it misses the genre's point [New Scientist]
- Do weeds really love poor soil? Not if you look at the science [New Scientist]
- Life-friendly molecules are leaking out of Jupiter's giant moon Europa, Galileo images hint [Live Science]
- Psychedelic causes similar brain state to meditation [New Scientist]
- 'Behemoth star,' previously thought to be dying, is 'rising from the ashes' like a phoenix [Live Science]
- New map shows weird magnetic anomaly lurking beneath Australia's Northern Territory [Live Science]
- A new way to control light could boost future wireless tech [Science Daily]
- New nasal vaccine shows strong protection against H5N1 bird flu [Science Daily]
- Record-breaking quantum simulator could unlock new materials [New Scientist]
- The overlooked nutrition risk of Ozempic and Wegovy [Science Daily]
- Expansion Microscopy Has Transformed How We See the Cellular World [Quanta Magazine]
- 'Nitrogen fixing' trees could help tropical forests bounce back, research suggests [Live Science]
Space
- It's time to think about human reproduction in space, scientists urge [Space.com]
- Watch dead neutron stars smash together in new NASA supercomputer simulation [Space.com]
- Star Trek needs to go back to 20+ episode seasons — and there's never been a better time [Space.com]
- Photographer captures rare aurora over Brazil during intense geomagnetic storm (photo) [Space.com]
- Astronomers relieved as industrial plant threatening Earth's darkest sky gets cancelled [Space.com]
- A monstrous sunspot 15 Earth's wide is currently facing Earth: Here's how to see it for yourself [Space.com]
- Sun unleashes colossal X4.2 solar flare, knocking out radio signals across Africa and Europe (video) [Space.com]
- James Webb Space Telescope finds most distant galaxy ever detected: 'It looks nothing like what we predicted' [Space.com]
- Unlock a brand-new world of British sci-fi with a VPN [Space.com]
- NASA satellite watches January's polar vortex | Space photo of the day for Feb. 4, 2026 [Space.com]
- Is Jupiter on a diet? New measurements say it's smaller than we thought [Space.com]
- A 'cold Earth' exoplanet just 146 light-years away might be in its star's habitable zone — if it exists [Space.com]
- With the Mandalorian and Grogu movie arriving in our galaxy soon, start building the excitement with this fantastic Lego set [Space.com]
- Explore Mars’s Flaugergues Crater [ESA]
Asia
- Military Proxy Party Declared Lopsided Victor in ‘Sham’ Myanmar Election [The Diplomat]
- As It Ages, Southeast Asia Needs a 4-Day Workweek [The Diplomat]
- Can Pakistan and China Revive Their ‘All-Weather Friendship’? [The Diplomat]
- Oyu Tolgoi: Mongolia’s High-Stakes Clash With Rio Tinto [The Diplomat]
- Traffic Jam at Kazakh-Kyrgyz Border Result of Increased Inspections [The Diplomat]
- ‘Dancing in Shackles’: China’s Vibrant – But Constrained – Internet Culture [The Diplomat]
- Is New Zealand’s Defense and Intelligence Policy Aligning With AUKUS in All But Name? [The Diplomat]
- Karachaganak Arbitration Win Gives Kazakhstan New Leverage Over Big Oil [The Diplomat]
- New START’s Expiration Is a Win for China [The Diplomat]
- The Pandemic Roots of the Sino-Russian ‘No-Limits’ Friendship [The Diplomat]
- Kazakhstan’s New Draft Constitution: A State-Building Blueprint With External Consequences [The Diplomat]
- Japan’s Defense Policy Accelerates as Public Debate Lags Behind [The Diplomat]
- Did Trump Jump the Gun With the US-India Trade Deal Announcement? [The Diplomat]
Africa
- East Africa tries, again, to integrate its capital markets [The East African]
- MSF says airstrike hit its hospital in South Sudan’s Jonglei [The East African]
- South Sudan economy reels under cash shortages and conflict [The East African]
- Absa Bank pegs Ethiopia entry on less restrictive ownership rules [The East African]
- M23 claim failed drone attack on Kisangani airport [The East African]
- DRC takes on Rwanda as rivalry spills into Francophonie race [The East African]
South America
- Milei’s dilemma: Trading with China while pleasing Trump [Buenos Aires Times]
- Colombia’s paramilitary successors suspend peace talks [Colombia Reports]
- Argentine court requests Maduro’s extradition from the United States [Buenos Aires Times]
- Argentina is key US partner for rare earth extraction, says Rubio [Buenos Aires Times]
- Milei pushes dollar loans for all, ending a taboo in Argentina [Buenos Aires Times]
- Colombia’s illegal armed groups have 27,000 members: NGO [Colombia Reports]
- Cristina Fernández de Kirchner’s lawyers seek annulment of 'Cuadernos' graft mega-trial [Buenos Aires Times]
- Peru agrees to extradite to Argentina main suspect in triple homicide case [Buenos Aires Times]
- Analysis: Petro’s visit to the White House [Colombia Reports]
- Milei first in line as Argentina launches updated ID card, passport [Buenos Aires Times]
- Petro has “confusing,” but “positive” meeting with Trump after year-long tensions [Colombia Reports]
UK News
- How much did Starmer really know about Mandelson’s ties to Epstein? [The Guardian UK]
Top Journals
- Elective Cesarean Section for Maternal Preference [NEJM]
- Floppy Eyelid Syndrome [NEJM]
- A Matter of Time [NEJM]
- Beta-Blockers after Myocardial Infarction — Toward Personalized Management [NEJM]
- Exploring a New “Reef” in Dyslipidemic Risk Reduction [NEJM]
- Freedom of Speech and the Viability of Science — Dr. Jeremiah Stamler’s Fight against HUAC [NEJM]
- Functional Dyspepsia [NEJM]
- Spontaneous Heparin-Induced Thrombocytopenia after Total Hip Arthroplasty [NEJM]
- Phase 1 Trial of CRISPR-Cas9 Gene Editing Targeting ANGPTL3 [NEJM]
- Sacituzumab Govitecan in Advanced Triple-Negative Breast Cancer [NEJM]
- More on Cold Perfusion vs. Static Cold Storage of Deceased-Donor Kidneys [NEJM]
- Sevabertinib in Advanced HER2-Mutant Non–Small-Cell Lung Cancer [NEJM]
- Hypertonic Saline or Carbocisteine in Bronchiectasis [NEJM]
- Mavacamten in Nonobstructive Hypertrophic Cardiomyopathy [NEJM]
- The Inherited Basis of Coronary Artery Disease [NEJM]
- A Placebo-Controlled Trial of the Oral PCSK9 Inhibitor Enlicitide [NEJM]
- Antigenic Drift and Antivaccine Shift in the 2025–2026 Influenza Season [NEJM]
- The Growing Success of Medicare Drug-Price Negotiation [NEJM]
- Space dust reveals rapid evolution after dino-killing asteroid [Science]
- Synapse-specific and plasticity-regulated AMPA receptor mobility tunes synaptic integration [Neuron]
Long Reads
- Stewart Brand on How Progress Happens [The New Yorker]
- The Pie and Mash Crisis: Can the Original Fast Food Be Saved? [Longreads]
- Sundance Is a Feast of World Cinema [The New Yorker]
- Astronauts Are Going Back to the Moon For The First Time in Half a Century [Longreads]
- Daily Cartoon: Wednesday, February 4th [The New Yorker]
- How Jeff Bezos Brought Down the Washington Post [The New Yorker]
- The Best Books of 2026 So Far [The New Yorker]
- The Best Books of 2025 [The New Yorker]
- Being in the world: rules and risk [Aeon]
- Animals Say Hello, but Do They Say Goodbye? [The New Yorker]
- Gay Figure Skaters Pave Their Own Way in “Icebreakers” [The New Yorker]
- The Good Old Days of Sports Gambling [The New Yorker]
- Recreating the Smells of History [Longreads]
Protein Data Bank
- 3D 10AD: Cryo-EM structure of the human BK channel bound to the agonist NS1619
- 3D 10ID: Membrane-bound, reversed VP5* trimer (rotavirus spike protein)
- 3D 10JU: Crystal Structure of serine/threonine-protein kinase (AEK1) T376D, S395D Mutant from Trypanosoma brucei (AMP-PNP)
- 3D 10KE: Crystal structure of Capsular polysaccharide biosynthesis protein from Bordetella pertussis in complex with NAD and uridine-diphosphate-n-acetylgal...
- 3D 10LG: Crystal structure of Streptococcus thermophilus SHP pheromone receptor Rgg3 in complex with Rgg3bp13
- 3D 21FB: Structure of minor species of Abeta fibrils from AppNL-FPsen1P117L mice
- 3D 21IE: The MIDN Catch-IRF4 (A8S) fusion protein
- 3D 21IK: The MIDN Catch-IRF4 (V2T) fusion protein
- 3D 21IP: The MIDN Catch-IRF4 (A8C) fusion protein
- 3D 22GA: Crystal structure of sorghum sulfotransferase LGS1 reveals sulfation-assisted BC-ring formation in strigolactone biosynthesis
PDB Nitrogen Cycle
- 3D 9CWY: Crystal structure of HLA-A*03:02 in complex with a wild-type PIK3CA peptide
- 3D 9CWZ: Crystal structure of HLA-A*03:02 in complex with a mutant PIK3CA peptide
- 3D 9G7L: Structure of the proline-rich binding domain of Tesup-1 in complex with dZfc3h1 peptide
- 3D 9G83: Respiratory supercomplex CI1-CIII2-CIV2-(cbb3)1 from alphaproteobacterium
- 3D 9G9Y: Respiratory supercomplex CI2-CIII2-CIV2 (megacomplex) from alphaproteobacterium
- 3D 9G9Z: Respiratory supercomplex CI1-CIII2-CIV1 (respirasome) from alphaproteobacterium
- 3D 9GAE: Respiratory supercomplex CI1-CIII2-CIV2 from alphaproteobacterium
- 3D 9I3X: Structure of anti-EV71 human monoclonal antibody 16-2-11B Fab
- 3D 9I4D: Structure of anti-EV71 human monoclonal antibody 17-2-2B Fab
- 3D 9I4W: Structure of carbamoylated recombinant human butyrylcholinesterase by the biscarbamte 5-(1-hydroxy-2-(piperidin-1-yl)ethyl)-1,3-phenylene bis(piper...
PDB Photosynthesis
- 3D 9G83: Respiratory supercomplex CI1-CIII2-CIV2-(cbb3)1 from alphaproteobacterium
- 3D 9G9Y: Respiratory supercomplex CI2-CIII2-CIV2 (megacomplex) from alphaproteobacterium
- 3D 9G9Z: Respiratory supercomplex CI1-CIII2-CIV1 (respirasome) from alphaproteobacterium
- 3D 9GAE: Respiratory supercomplex CI1-CIII2-CIV2 from alphaproteobacterium
- 3D 9H3G: Structure of the Arabidopsis thaliana 80S ribosome in complex with P- and E-site tRNAs and mRNA
- 3D 9H6I: Structure of the Arabidopsis thaliana 80S ribosome in complex with P- and E-site tRNAs, mRNA, and thermospermine
- 3D 9HES: Structure of the Arabidopsis thaliana 80S ribosome OVAC mutant in complex with P- and E-site tRNAs, mRNA, and thermospermine
- 3D 9HMW: Structure of the Arabidopsis thaliana 80S ribosome OVAC mutant in complex with P- and E-site tRNAs and mRNA
- 3D 9I26: inactive Form II Rubisco from Rhodospirillum rubrum
- 3D 9I27: activated Form II Rubisco from Rhodospirillum rubrum with bound Magnesium and CABP
PDB PFAS Degradation
- 3D 9CWY: Crystal structure of HLA-A*03:02 in complex with a wild-type PIK3CA peptide
- 3D 9I3X: Structure of anti-EV71 human monoclonal antibody 16-2-11B Fab
- 3D 9QCH: Complex of Ovine Serum Albumin with Cephalosporin C
- 3D 9RPL: Lactobacillus acidophilus SlpA self assembly domains I-II (aa 49-308)
- 3D 9S42: Complex of Equine Serum Albumin with Hydrolyzed Ampicillin
- 3D 9S43: Complex of Equine Serum Albumin with Oxacillin
- 3D 9S73: Complex of Equine Serum Albumin with Ampicillin
- 3D 9SC5: Complex of Ovine Serum Albumin with Oxacillin
- 3D 9SDJ: Complex of Ovine Serum Albumin with Hydrolyzed Ampicillin
- 3D 9DAY: Crystal Structure of the Transcriptional Regulator HcpR from Porphyromonas Gingivalis
Project Gutenberg
- A Study in Scarlet EPUB PDF
- Persuasion EPUB PDF
- The Time Machine EPUB PDF
- Dubliners EPUB PDF
- The Complete Poetical Works of Percy Bysshe Shelley EPUB PDF
- The Republic EPUB PDF
- Adventures of Huckleberry Finn EPUB PDF
- The Yellow Wallpaper EPUB PDF
- Grimms' Fairy Tales EPUB PDF
- Little Women EPUB PDF
- Les Miserables EPUB PDF
- The Iliad EPUB PDF
- The Souls of Black Folk EPUB PDF
- The Divine Comedy EPUB PDF
- Jane Eyre EPUB PDF
GitHub bioRxiv
-
Zhaojp-Frank/AwesomePaper-for-AI
10
Unknown
Awesome system papers for AI
-
RagnarGrootKoerkamp/sassy
99
Rust
Fast approximate string searching
-
eugenevinitsky/lea
9
TypeScript
bluesky portal for researchers
-
soedinglab/PMGen
21
Python
peptide-MHC modeling, binding prediction, and protein design.
-
rpatrik96/bibtexupdater
61
Python
Tools for managing BibTeX bibliographies: automatically update preprints to publ...
-
bytedance/Protenix
1561
Python
Toward High-Accuracy Open-Source Biomolecular Structure Prediction.
-
mdozmorov/RNA-seq_notes
53
Unknown
A continually expanding collection of RNA-seq tools
-
Hawksight-AI/semantica
657
Python
Semantica🧠: Open-Source Semantic Layer & Knowledge Engineering Framework for bui...
-
sagar87/spatialproteomics
39
Python
Spatialproteomics is a light weight wrapper around xarray with the intention to ...
-
cafferychen777/mLLMCelltype
631
R
Cell type annotation for single-cell RNA-seq using multi-LLM consensus
Synthetic Biology
- Protein-inducible ribosomal frameshifting enables programmable translational control for genetic circuit design in Escherichia coli.
- A validation for sex differences in gut microbiome of essential hypertension based on cohort analysis.
- KDM5B cooperates with CRL4B complex to promote the tumorigenesis of ER+ breast cancer via regulating cholesterol metabolism.
- Nitrogen starvation induces arbuscular mycorrhizal fungi to optimize resource allocation in sugarcane roots via suppression of basal metabolism.
- Limitations of traditional mycotoxin control and biotechnological advances toward sustainable solutions.
- bHLH transcription factors: Key regulators of bioactive component biosynthesis in medicinal plants.
- Characterization of Usher Syndrome Type 2-Associated Proteins in the Retina via Affinity Purification-Mass Spectrometry.
- Combining metabolic engineering and fermentation optimization to achieve cost-effective oil production by Cutaneotrichosporon oleaginosus.
- Preferential use of alkyl-acyl phosphatidylinositol for GPI biosynthesis and diagnostic potential of lipidomics for inherited GPI deficiencies.
- Compartmentalized branched-chain amino acid metabolism orchestrates colorectal cancer dissemination via an UMP-vimentin axis.
- Refactoring two-component systems for tunable gene expression regulation and upgraded bacterial sensing.
- Rewriting endogenous human transcripts with dual CRISPR-guided 3' trans-splicing.
- L-phenylalanine induces cutin and wax biosynthesis in muskmelon fruit epidermis via fatty acid and triterpenoid pathways.
- Molecular mechanism of SmERF B3-4 in regulating lignin biosynthesis by modulating Sm4CL11 in Salix matsudana.
- Nitrogen enhances cadmium phytoremediation in poplar via physiological, molecular, and rhizobacterial mechanisms.
Biotechnology
- AAV NRF2 Gene Therapy Preserves Retinal Structure and Function in Rodent Models of Oxidative Damage.
- PTPN2 deficiency amplifies inflammatory signalling and impairs functional maturation of human stem cell-derived islets.
- Ex vivo long-term expansion of human hematopoietic stem and progenitor cells as a tool for modeling vector integration sites and clonality.
- Current Advances and Applications of Retinal Organoids.
- A combinatorial synthetic strategy for developing genome-editing protein-delivery agents targeting mouse retina.
- Sporoplasm: The initial cell in microsporidia life cycle.
- Limitations of traditional mycotoxin control and biotechnological advances toward sustainable solutions.
- Field-deployable CRISPR-Cas variants for rapid on-site detection of plant pathogens.
- CRISPR/Cas9-Engineered Salmonella Phage Displaying Antimicrobial Peptide LL37 for Enhanced Antibacterial Activity.
- Rewriting endogenous human transcripts with dual CRISPR-guided 3' trans-splicing.
- CRISPR-initiated exponential amplification on fluorescently-barcoded microspheres for deep learning-assisted multiplexed HPV detection.
- Highly efficient gene editing via targeted Cas9 insertion into chicken housekeeping gene.
- Dual knockout of Fas and TCRα in Jurkat reporter cells enables highly sensitive identification of antigen-specific TCRs.
- CRISPR/Cas9-mediated SiZAT12 mutagenesis enhances drought tolerance without yield penalty in foxtail millet (Setaria italica).
- CRISPR mediated inactivation of OsPLDβ1 phospholipase enhances drought tolerance by upregulating stress-related genes and antioxidant enzymes in rice.
AI & Machine Learning
- Integrative cross-tissue and spatially resolved single-cell profiling uncovers tumour-educated inflammatory remodelling of tissue-resident macrophage ecosystem with immunotherapeutic prognostic significance in pan-cancer.
- Advances in the postoperative care of the liver transplant recipient.
- Exploring the Ethical Dimensions of AI-Driven Patient Monitoring in Critical Care Nursing: A Systematic Review.
- Spectral Representation of Neurochemicals With Phase, Frequency Offset, and Lineshape Invariance: Application to JPRESS for In Vivo Concentration and T(2) Mapping by Deep Learning.
- Introducing AutoML framework for Drug-Drug Interaction Prediction: Application of AutoGluon.
- Identification of immune-related genes and serum miR-100-5p in idiopathic inflammatory myopathy-related heart failure by integrated bioinformatics analysis and clinical validation.
- Artificial intelligence in emergency surgery: a scoping review within the artificial intelligence in emergency and trauma surgery (ARIES) project.
- TFAP2A transcriptionally regulates B3GALT2 to affect gouty arthritis progression through pyroptosis: a study based on machine learning and multi-omics integration analysis.
- Artificial intelligence in medical ethics education: a descriptive study of eight models in multiple choice question generation.
- Performance of machine learning algorithms in diffusion tensor imaging of movement disorders: an exploratory meta-analysis.
- AMP-CapsNet: a multi-view feature fusion approach for antimicrobial peptide prediction using capsule networks.
- Explainable machine learning for depression risk prediction in adults with obesity: development of an online tool.
- AI-driven biomarker learning for the early diagnosis of neurodegenerative diseases: ABLEDx.
- AI-driven 3D virtual surgical planning in total hip arthroplasty: a machine learning approach for precision implant positioning and improved clinical outcomes.
- Ethical concerns and strategies for implementing artificial intelligence in healthcare: a review of empirical studies.
Neuroscience
- Time-weighted lactate and glucose-lactate ratio outperform static values in ICU mortality prediction after traumatic brain injury: a retrospective cohort study.
- Clinical outcomes of short-segment cement-augmented pedicle screw fixation combined with vertebroplasty in patients with stage III Kummell's disease.
- Bridging the blood-brain barrier: strategies to improve delivery of biologics to tumors in the brain.
- Magnesium silicate nanosheets enable sustained hydrogen release to attenuate secondary brain injury following intracerebral hemorrhage.
- Exercise-derived exosomes: molecular mediators of systemic health and disease therapy.
- AI-driven biomarker learning for the early diagnosis of neurodegenerative diseases: ABLEDx.
- Risk factors for neonatal brain injury in neonates born to mothers with preeclampsia: a retrospective study.
- DefaceQA - automated quality assessment of brain MRI defacing software.
- A 3D gut-brain-vascular platform for bidirectional crosstalk in gut-neuropathogenesis.
- Target-Specificity and repeatability in neuro-cardiac-guided TMS for heart-brain coupling.
- Corrigendum to Simple quantitative planimetric measurement of nigrosome-1 for clinical settings [Journal of the Neurological Sciences 454 (2023) 120857].
- Corrigendum to "From ancient fears to airborne threats: fMRI insights into neural fear responses" [Brain Cogn. 191 (2025) 106371].
- Understanding the Older Brain in Depression.
- Beta-Caryophyllene Restores Liver-Brain Axis Integrity in Thioacetamide-Induced Hepatic Encephalopathy: Behavioral and Molecular Insights.
- Dexamethasone as an Adjuvant to Erector Spinae Plane Block Is Associated With Improved Neuromonitoring Parameters and Analgesia in Pediatric Spine Surgery.
Climate Science
- To ABG or Not to ABG-Reducing Inappropriate Arterial Blood Gas Testing in Critical Care.
- Climate change drives convergent evolution of root traits on Sky Island climate relicts.
- Climate change and pesticide resistance: A synthesis on emerging mechanisms and evolutionary dynamics.
- Insect declines: Challenges and solutions.
- Sustainable application of waste residue from coal gasification process in low-carbon cement: multiscale evaluation, hydration behavior, mechanical performance, and environmental assessment.
- Closing the loop: A systematic review of artificial intelligence in circular e-waste management.
- A promising biotic ligand model for predicting the phytotoxicity of hexavalent chromium (Cr(VI)) during seawater intrusion: Roles of sulfate, chloride, and Cr(VI) species.
- Advances in carbon capture, conversion, and utilization: A review of sustainable chemical production pathways.
- Electron beam-induced decomposition of nitrous oxide (N(2)O) and the critical role of oxygen.
- Physiology and behaviour of eastern oysters (Crassostrea virginica) and soft-shell clams (Mya arenaria) under hypoxic and heatwave conditions.
- Deeper waters, more calcifiers: Spatial variation in benthic assemblages highlight conservation challenges in sub-Antarctic Marine Protected areas.
- Green and red nets showed opposite influence on carotenoid accumulation in citrus by differential regulation of CitPSY and CitCCD4 gene expression.
- CRISPR mediated inactivation of OsPLDβ1 phospholipase enhances drought tolerance by upregulating stress-related genes and antioxidant enzymes in rice.
- Combined "omics" and physiological approaches highlight the roles of the GABA shunt and mitochondria-related functions in rice seed longevity.
- Life Cycle Assessment of road expansion: Baseline environmental impacts in El Salvador.
Medicine
- Integrative cross-tissue and spatially resolved single-cell profiling uncovers tumour-educated inflammatory remodelling of tissue-resident macrophage ecosystem with immunotherapeutic prognostic significance in pan-cancer.
- ALKBH5 Orchestrates Ferroptosis-Driven Tumor Suppression: An LLM-Powered Discovery in Prostate Cancer.
- Mapping the clinical landscape of multifunctional CAR T cells: targets, trends, and synergies.
- Acute Graft-Versus-Host Disease After Deceased-Donor Liver Transplantation: A Case Report.
- Therapeutic Efficacy of Oral Tofacitinib in Pediatric Prurigo Nodularis: A Case Series With a Review of Literature.
- Janus Kinase Inhibitors as a Therapeutic Option for Chronic Spontaneous Urticaria Refractory to Antihistamines and Omalizumab: A Case Series.
- Methods and Instruments to Measure ICU Healthcare Professionals' Workload Related to Medical Technology-Protocol for a Scoping Review.
- VPS4A activates glycolytic metabolism via MYO1C to promote radioresistance in ESCC.
- The utility of urine lipoarabinomannan as a tuberculosis treatment monitoring tool in people living with HIV.
- Time-weighted lactate and glucose-lactate ratio outperform static values in ICU mortality prediction after traumatic brain injury: a retrospective cohort study.
- CI-994 is a dual modulator of class I HDACs and Wnt/β-catenin signaling for the treatment of Alzheimer's disease.
- In vitro assays for investigating the immunomodulatory properties of human mesenchymal stromal cells.
- Refining the PTV margin determination for VMAT SBRT lung treatment through moving target dose model to account for respiratory motion uncertainty.
- A biohybrid platform integrating bacterial propulsion and photoresponsive nanomedicine for adequate intratumoral drug delivery.
- The minimally invasive approach for lateral malleolus fractures plating demonstrating less pain, shorter operative time and earlier discharge compared to open approach: a prospective randomized controlled trial.
Genomics
- Integrative cross-tissue and spatially resolved single-cell profiling uncovers tumour-educated inflammatory remodelling of tissue-resident macrophage ecosystem with immunotherapeutic prognostic significance in pan-cancer.
- Outbreak investigation and genomic analysis reveal hidden transmission networks of KPC-2-producing Enterobacterales in a South Korean hospital.
- RT-ICI therapy induces a distal immunometabolic axis that shapes systemic macrophage polarization and enhances local T cell immunity.
- Genetic affinities between the ancient Greek colony of Amvrakia and its metropolis.
- Antimicrobial resistance and virulence of Enterococcus faecium isolates from a traditionally fermented dairy beverage from Uganda.
- Developmental neurotoxicity of thyroid hormone system-disrupting chemicals: a systems-level exploration using multi-omics approach.
- The use of new approach methodologies (high-throughput transcriptomics) to study nanoagrochemicals: mechanisms of toxicity of a commercial copper oxychloride to soil model invertebrates (Enchytraeus crypticus).
- Estrogen receptor β target gene expression reveals novel repressive functions in aggressive breast cancer.
- Modeling and application of alzheimer's disease complex trait prediction based on multi-task learning.
- Quorum-quenching lactonase AiiO from Ochrobactrum quorumnocens B44 isolated from bark compost attenuates the virulence of plant pathogens.
- Inositol Hexaphosphate and Inositol Prevent WD/CCl₄-Induced Metabolic Dysfunction-Associated Steatohepatitis in Mice.
- Isolation, characterization and dairy application of a novel bacteriophage fBSPA4 against Salmonella enterica.
- Serum procalcitonin: A novel tumor biomarker for diagnosis and disease monitoring in fibrolamellar hepatocellular carcinoma.
- ROS-Driven Rewiring of Hippo-Inflammation-Polycomb Axis by PFOA in 2D and 3D Lung Epithelial Models.
- GenomeSyn-II: a comparative genomics framework integrating synteny visualization.
Immunology
- Galectin-3 in the Lateral Ventricle Regulates Immune Functions.
- LpqH-tagged microvesicles as mRNA vaccine carriers for specific delivery of mRNA into macrophages.
- From Amphiphiles to mRNA platforms: emerging vaccination strategies for pancreatic cancer.
- Sex differences in disease severity and immune responses in murine and human inflammatory arthritis.
- Computational design of a novel multi-epitope vaccine candidate against group A rotavirus.
- AMP-CapsNet: a multi-view feature fusion approach for antimicrobial peptide prediction using capsule networks.
- Association between COVID-related health literacy and vaccine acceptance: results of a nationwide cross-sectional study in Hungary.
- Prevalence of herpes zoster in individuals who have received COVID-19 vaccine and/or had COVID-19: a cross-sectional study.
- Forecasting and quantifying the role of vaccination strategies in the 2025 Texas measles outbreak: a modeling and time series analysis approach.
- Randomized pilot study of camrelizumab with or without autologous cytokine-induced killer cells in refractory clear cell renal cell carcinoma.
- Balancing innovation and accessibility in infection imaging: lessons from the [(99m)Tc]Tc-besilesomab paradox.
- Cellular immune response following homologous and heterologous BNT162b2 booster vaccination after primary immunization with BNT162b2 and CoronaVac respectively.
- Phase I Study Evaluating a Monoclonal Fc-Silenced SARS-CoV-2 Antibody in Patients With Moderate-to-Severe COVID-19.
- Contextualizing the Development of Anti-HER2 Therapies for Patients with Advanced Urothelial Carcinoma.
- Two vaccine-associated measles cases: Transmission or coincidental cases?
Microbiology
- Galectin-3 in the Lateral Ventricle Regulates Immune Functions.
- Plant diversity induces shifts from microbial generalists to specialist by enhancing niche differentiation, microbiome connectivity, and network stability in a temperate grassland.
- Species-level dynamics of gastric microbiome after Helicobacter pylori eradication in high-risk Mongolian population.
- Temporal and spatial shifts in the foliar fungal endophyte community of Norway spruce (Picea abies) over 150 years in Finland.
- Quantifying lifetime risk for 1,401 infectious diseases across the diabetes spectrum using a Bayesian approach.
- First report of Candidozyma auris in Vietnam.
- Characteristics comparative of gut microbiota in four small mammal species co-occurring in the Hengduan Mountains: differences in environmental adaptation strategies between alien and endemic species.
- A validation for sex differences in gut microbiome of essential hypertension based on cohort analysis.
- Low-inflammatory response phenotypes in elderly urinary tract infections: pathogen type, antimicrobial resistance, and comorbidity-associated risk profiles.
- An aptamer-based "Gate-lock-key" strategy for metal-organic framework nanozyme-catalyzed colorimetric detection of multidrug-resistant bacteria.
- Point-of-use colorimetric detection of Escherichia coli in food matrices with DNAzyme crosslinked hydrogels.
- Enhanced resistance and resilience of anaerobic digestion microbiome after single and dual short-term disturbances.
- Microbiome by transcriptome interactions triggered by a switch to an alternative diet in Nellore cattle.
- Quorum-quenching lactonase AiiO from Ochrobactrum quorumnocens B44 isolated from bark compost attenuates the virulence of plant pathogens.
- Management of infections caused by Gram-negative bacteria in severely immunocompromised hosts employing Outpatient Parenteral Antimicrobial Therapy (OPAT): Preliminary evidence from a real-world observational study.
Evolutionary Biology
- Vertebrate-wide transcriptomic screening identifies immune cell-specific expression of the conserved OR-κ gene.
- A reference-free pipeline for detecting shared transposable elements from pan-genomes to retrace their dynamics in a species.
- Organellar genome evolution in Camellia tianeensis (Theaceae): comparative insights into RNA editing, codon usage, and DNA transfer between chloroplast and mitochondrion.
- Spatio-temporal evolution and driving factors of China's foreign aid: a country-level analysis.
- Climate change drives convergent evolution of root traits on Sky Island climate relicts.
- High-performance temperature regulation of nonlinear CSTRs via a hybrid stellar oscillation optimizer and differential evolution-based PID-F control.
- Convergent extreme reductive evolution in ancient planthopper symbioses.
- Ancient gene flow shapes phylogenetic discordance in a genus of wood-warblers (Aves: Parulidae: Leiothlypis).
- Out of North Africa: Evolution and biogeography of Afro-Arabian dwarf tarantulas (Theraphosidae, Ischnocolinae).
- Evolution of Pre-Genetic Semantic Information in Protocells Under Variable Inheritance Fidelity.
- Regulating hydrogen-bond network via a low-viscosity electrolyte for hydrogen evolution reaction-free aqueous sodium-ion batteries.
- Highly selective photocatalytic conversion of CO(2) to hydrocarbons, H(2) evolution, and photodegradation of CV dye using SbSI and SbSeI as catalysts.
- RSM-optimized Mg/Al-LDH biochar composite for enhanced phosphorus removal: Insights into interlayer structure evolution and adsorption mechanism.
- Research note: Molecular characteristics and genetic evolution of H1N1 avian influenza virus from wild birds in Shanghai, China.
- Deterministic Evolution of Aptamers via a Microfluidic-Integrated Robotic Platform Using Complex Exosomes as Targets.
Molecular Ecology
- Plant diversity induces shifts from microbial generalists to specialist by enhancing niche differentiation, microbiome connectivity, and network stability in a temperate grassland.
- Systematic revision of Paralongidorus (Nematoda: Longidoridae) based on molecular and morphological evidence, with the description of a new species from Spain.
- Drivers of Scarabaeidae (Coleoptera) attraction: the roles of habitat diversity and bait type evaluated through EUNIS habitat classes.
- Wild edible plants and associated indigenous knowledge among the Setswana-speaking people of North West Province in South Africa.
- First record of Penicilliopsis clavariiformis Solms. on seeds of Diospyros ferrea (Willd.) Bakh. from the Northern Western Ghats, India.
- Corrigendum to "Biodiversity-dependent invasiveness of naive river epilithic biofilms by anthropogenic antibiotic resistance at the interface between the human, animal and environmental spheres" [Sci. Total Environ. Volume 1012 (2026) 181237].
- Diversity and pathogen surveillance in chigger mites across Brazil's five biogeographic regions.
- Insect declines: Challenges and solutions.
- Hydrological period conversions induce micro-eukaryotic community homogenization along the eastern route of China's South-to-North Water Diversion Project.
- Effects of mycorrhizal dominance on species diversity and carbon stock in a large temperate forest region.
- Enhancing the effectiveness of behavioral intervention through high-performing media and the RE-AIM framework: Randomized field experiments on reducing unintentional propagule introduction.
- A preliminary study and assessment of the effects of beaver engineering on river condition and its relevance for biodiversity net gain.
- Deeper waters, more calcifiers: Spatial variation in benthic assemblages highlight conservation challenges in sub-Antarctic Marine Protected areas.
- Rainfall alters network structure, while fragmentation results in the breakdown of a mixed-species group of birds.
- Unlocking the potential of other effective area-based conservation measures (OECMs) for achieving conservation targets: A global scoping review.
arXiv Physics
- PDF Explosive eruption cycles in a rotating Z-pinch
- PDF Modeling integrated frequency shifters and beam splitters
- PDF Westcott $g$ Factors Extended to Arbitrary Neutron Energy Spectra
- PDF Quantum noise scaling in continuously operating multiparameter sensors
- PDF Efficient net-gain integrated optical parametric amplifier in the quantum regime
- PDF Extended Rydberg Lifetimes in a Cryogenic Atom Array
- PDF Poisson Log-Normal Process for Count Data Prediction
- PDF Photonic neuromorphic processing with coupled spiking silicon microrings
- PDF The Effects of Non-ideal Mixing in Planetary Magma Oceans and Atmospheres
- PDF Higher-order adaptive behaviors outperform pairwise strategies in mitigating contagion dynamics
- PDF Active Soft-Impact Oscillator: Dynamics of a Walking Droplet in a Non-Smooth Potential
- PDF Self-Portrait of the Focusing Process in Speckle: III. Tailoring Complex Spatio-Temporal Focusing Laws To Overcome Reverberations in Reflection Imaging
- PDF Self-Portrait of the Focusing Process in Speckle: I. Spatio-Temporal Imaging of Wave Packets in Complex Media
- PDF On particle dynamics in steady axial rotor flows
- PDF An FWCI decomposition of Science Foundation Ireland funding
arXiv Mathematics
- PDF Diffusion Model's Generalization Can Be Characterized by Inductive Biases toward a Data-Dependent Ridge Manifold
- PDF Towards uncertainty quantification of a model for cancer-on-chip experiments
- PDF Convex unions and completions from simplicial pseudomanifolds
- PDF Optimism Stabilizes Thompson Sampling for Adaptive Inference
- PDF Excursion decomposition of the XOR-Ising model
- PDF Vector-Valued Singular Integrals on Locally Doubling Spaces
- PDF Computing Diffusion Geometry
- PDF Lattices from Pointed Building Sets: Generalized Ornamentation Lattices
- PDF Categories graded by group homomorphisms
- PDF Finite time singularities in the Landau equation with very hard potentials
- PDF The Signed Wasserstein Barycenter Problem
- PDF Normalization of ReLU Dual for Cut Generation in Stochastic Mixed-Integer Programs
- PDF Inverse Depth Scaling From Most Layers Being Similar
- PDF Stability of the $L^{p}$-Poincaré inequality for the Lebesgue and Gaussian probability measures with explicit geometric dependency
- PDF Global solvability and stabilization in multi-dimensional small-strain nonlinear thermoviscoelasticity
arXiv Computer Science
- PDF Shared LoRA Subspaces for almost Strict Continual Learning
- PDF Pseudo-Invertible Neural Networks
- PDF Predicting Camera Pose from Perspective Descriptions for Spatial Reasoning
- PDF DyTopo: Dynamic Topology Routing for Multi-Agent Reasoning via Semantic Matching
- PDF SwimBird: Eliciting Switchable Reasoning Mode in Hybrid Autoregressive MLLMs
- PDF CommCP: Efficient Multi-Agent Coordination via LLM-Based Communication with Conformal Prediction
- PDF Thinking with Geometry: Active Geometry Integration for Spatial Reasoning
- PDF DFlash: Block Diffusion for Flash Speculative Decoding
- PDF InterPrior: Scaling Generative Control for Physics-Based Human-Object Interactions
- PDF V-Retrver: Evidence-Driven Agentic Reasoning for Universal Multimodal Retrieval
- PDF Can vision language models learn intuitive physics from interaction?
- PDF Splat and Distill: Augmenting Teachers with Feed-Forward 3D Reconstruction For 3D-Aware Distillation
- PDF PhysicsAgentABM: Physics-Guided Generative Agent-Based Modeling
- PDF AP-OOD: Attention Pooling for Out-of-Distribution Detection
- PDF Curiosity is Knowledge: Self-Consistent Learning and No-Regret Optimization with Active Inference
arXiv Quantitative Biology
- PDF Mechanisms of AI Protein Folding in ESMFold
- PDF Characterizing Human Semantic Navigation in Concept Production as Trajectories in Embedding Space
- PDF Intermittent precipitation and spatial Allee effects drive irregular vegetation patterns in semiarid ecosystems
- PDF Somatic Mechanotherapy Activates a Spatiotemporally Synchronized CPTC Wnt Axis for Gut Regeneration
- PDF Specieslike clusters based on identical ancestor points
- PDF Learning virulence-transmission relationships using causal inference
- PDF Combination therapy for colorectal cancer with anti-PD-L1 and cancer vaccine: A multiscale mathematical model of tumor-immune interactions
- PDF Optimal Harvesting in Stream Networks: Maximizing Biomass and Yield
- PDF A novel scalable high performance diffusion solver for multiscale cell simulations
- PDF Protein Autoregressive Modeling via Multiscale Structure Generation
- PDF Uncertainty in Island-based Ecosystem Services and Climate Change
- PDF BrainVista: Modeling Naturalistic Brain Dynamics as Multimodal Next-Token Prediction
- PDF Discovering Mechanistic Models of Neural Activity: System Identification in an in Silico Zebrafish
- PDF The impact of heterogeneity on the co-evolution of cooperation and epidemic spreading in complex networks
- PDF How seed banks evolve in plants: a stochastic dynamical system subject to a strong drift
arXiv Quantitative Finance
- PDF Universal approximation with signatures of non-geometric rough paths
- PDF On the Skew Stickiness Ratio
- PDF Optimal Risk-Sharing Rules in Network-based Decentralized Insurance
- PDF Music as an Asset Class
- PDF Fair Pricing in Long-Term Insurance: A Unified Framework
- PDF Sampled-Data Wasserstein Distributionally Robust Control of Multiplicative Systems: A Convex Relaxation with Performance Guarantees
- PDF DiffLOB: Diffusion Models for Counterfactual Generation in Limit Order Books
- PDF Quantum Speedups for Derivative Pricing Beyond Black-Scholes
- PDF Taming Tail Risk in Financial Markets: Conformal Risk Control for Nonstationary Portfolio VaR
- PDF Soft-Radial Projection for Constrained End-to-End Learning
- PDF A Novel approach to portfolio construction
- PDF Dual Attainment in Multi-Period Multi-Asset Martingale Optimal Transport and Its Computation
- PDF Habit Formation, Labor Supply, and the Dynamics of Retirement and Annuitization
- PDF Reliable Real-Time Value at Risk Estimation via Quantile Regression Forest with Conformal Calibration
- PDF The Innovation Tax: Generative AI Adoption, Productivity Paradox, and Systemic Risk in the U.S. Banking Sector