News
US News
- Nancy Guthrie update: Detailed timeline, $50K reward and "imposter" ransom arrest [Axios]
- Anthropic's newest AI model uncovered 500 zero-day software flaws in testing [Axios]
- Trump admin green lights rule making it easier to fire thousands of federal employees [Axios]
- Trump to launch TrumpRx drug discount site. Here's when [Axios]
- Scoop: U.S. and Russia agree to observe New START nuclear pact after expiration [Axios]
- "Schumer needs to get the hell out": House Democrats fume over DHS funding talks [Axios]
- Political violence and low pay are pushing young state lawmakers toward the exit [Axios]
- AI arms race approaches IPO reckoning [Axios]
- Washington Post cuts reignite concerns over Bezos ownership [Axios]
- NBCUniversal prepares for "Legendary February" [Axios]
- Dems outline 10 demands in letter to GOP leaders in ICE funding fight [Axios]
- Scoop: FBI chief ready to head to Tucson as Trump pledges help to find Savannah Guthrie's mom [Axios]
- Dems embrace "law and order" in ICE shutdown fight [Axios]
- Scoop: Cornyn unloading $10 million in last-minute ad blitz [Axios]
- Judge orders Musk to sit for deposition over DOGE, USAID shutdown [Axios]
EU News
- Storm disrupts Portugal as presidential run‑off election approaches [France 24]
- Ukraine says Starlink terminals used by Russia deactivated in blow to Moscow [France 24]
- US and Russia agree to reestablish military dialogue after Ukraine talks [France 24]
- Ukraine, Russia exchange prisoners of war for first time in months [France 24]
- UK's Starmer apologises to Epstein victims over Mandelson [France 24]
- Ukraine-Russia peace talks: 'No progress' on territory nor future security guarantees [France 24]
- UK's Starmer apologises to Epstein victims for appointing Mandelson US ambassador [France 24]
- 'Capitalist logic of Olympics: Sponsored by fossil fuels while pledging sustainability' [France 24]
Tech
- Two Titanic Structures Hidden Deep Within the Earth Have Altered the Magnetic Field for Millions of Years [Wired]
- OpenClaw reveals meaty personal information after simple cracks [The Register]
- AI companies want you to stop chatting with bots and start managing them [Ars Technica]
- X's latest Community Notes experiment allows AI to write the first draft [Engadget]
- The Switch 2 is getting a new Virtual Console (kind of) [Ars Technica]
- With GPT-5.3-Codex, OpenAI pitches Codex for more than just writing code [Ars Technica]
- NordVPN review 2025: Innovative features, a few missteps [Engadget]
- Loyalty Is Dead in Silicon Valley [Wired]
- ICE and CBP’s Face-Recognition App Can’t Actually Verify Who People Are [Wired]
- OpenAI chases business bucks with confusingly named Frontier platform [The Register]
- Everything we know about Valve's new Steam Machine [Engadget]
- Substack says intruder lifted emails, phone numbers in months-old breach [The Register]
- Prime members can play Alan Wake 2 for free on Luna [Engadget]
- Meta is giving its AI slop feed an app of its own [Engadget]
- Asia-based government spies quietly broke into critical networks across 37 countries [The Register]
- Project Hail Mary is getting its own LEGO set [Engadget]
- 9 Great Deals on WIRED-Approved Valentine’s Day Gifts (2026) [Wired]
- Stash or splash? Lawmakers ask NASA to find alternatives for International Space Station [The Register]
- The CIA stops publishing The World Factbook [Engadget]
- The 2026 Winter Olympics Will Have a Major Impact on the Region’s Snow [Wired]
Business
- Google blows nearly everything out of the water — including its AI budget [Quartz]
- How boosterism built America [Quartz]
- Bonds as bargaining chips: The $8 trillion selloff that could shake U.S. markets [Quartz]
- Scott Bessent won't rule out Trump eventually suing his new Fed pick [Quartz]
- Layoffs last month marked the worst January since 2009 [Quartz]
- Federal workers will be easier to fire under a new Trump administration move [Quartz]
- Selloffs in Bitcoin and silver continue to spiral, following Wall Street's woes [Quartz]
- The Muppet Show revival is universally loved — and perfectly timed for Disney [Quartz]
- How Pinterest's firing of two layoff-tracking engineers became a corporate morality play [Quartz]
- Hong Kong is getting its financial mojo back [The Economist]
- Untangling the ideas of Donald Trump’s Fed nominee [The Economist]
- Why the dollar may have much further to fall [The Economist]
- 10 cities that help young professionals kickstart their careers [Quartz]
- The 10 cheapest car brands to insure, according to Consumer Reports [Quartz]
Science
- Statins don't cause most of the side effects listed on their labels [New Scientist]
- The 'mono' virus raises the risk of MS and cancer in some. 22 genes hint at why. [Live Science]
- Spotted lanternflies are invading the US. They may have gotten their evolutionary superpowers in China's cities. [Live Science]
- Five stunning images from the Close-up Photographer of the Year awards [New Scientist]
- The toxic burden of pesticides is growing all around the world [New Scientist]
- Methane surge in 2020 was linked to lower pollution during lockdowns [New Scientist]
- Bonobo's pretend tea party shows capacity for imagination [New Scientist]
- Kanzi the bonobo could play pretend — a trait thought unique to humans [Live Science]
- Black hole outburst named 'Jetty McJetface' is one of the most energetic objects in the universe [Live Science]
- Martian meteorite that fell to Earth is full of ancient water, new scans reveal [Live Science]
- Fast-charging quantum battery built inside a quantum computer [New Scientist]
- Vegan toddlers can grow at the same rate as omnivores [New Scientist]
- 7,500-year-old deer skull headdress discovered in Germany indicates hunter-gatherers shared sacred items and ideas with region's first farmers [Live Science]
- Scientists uncover why psoriasis can turn into joint disease [Science Daily]
- This simple diet shift cut 330 calories a day without smaller meals [Science Daily]
- How well can AI and humans work together? Scientists are turning to Dungeons & Dragons to find out [Live Science]
- Doctors may be missing early signs of kidney disease [Science Daily]
- Endangered sea turtles hear ship noise loud and clear [Science Daily]
- Scientists just mapped the mutations that power cancer growth [Science Daily]
- Amazfit Active Max review: The best budget smartwatch of 2026? [Live Science]
Space
- This supermassive black hole jet is more powerful than the Death Star's laser [Space.com]
- NASA Selects Two Earth System Explorers Missions [NASA]
- The 10 bleakest space movies of all time [Space.com]
- Astrophotographer captures the 'Flaming Star Nebula' ablaze in deep-space (photo) [Space.com]
- Career Spotlight: Welder (Ages 14-18) [NASA]
- Watch Kanzi the bonobo pretend to have a tea party [Ars Technica Space]
- China joins race to develop space-based data centers with 5-year plan [Space.com]
- NASA’s SpaceX Crew-12 to Study Adaptation to Altered Gravity [NASA]
- This week's "Starfleet Academy" episode, "Series Acclimation Mil", is a near-perfect "DS9" sequel [Space.com]
- Now's your best chance to see Mercury all year — Here's what you need to know [Space.com]
- Hubble Spots Lens-Shaped Galaxy [NASA]
- This black hole "burps" with Death Star energy [Ars Technica Space]
- Could a toxic chemical in Mars dirt help us build a Red Planet base? [Space.com]
- The future of the Space Force in a competitive, congested and contested space environment [SpaceNews]
- A presidential greeting ahead of Sophie Adenot's first spaceflight [ESA]
- Deep space, dim objects: Why asteroid mining caught the Space Force’s eye [SpaceNews]
- NASA chief flies over Artemis 2 moon rocket | Space photo of the day for Feb. 5, 2025 [Space.com]
- Our round-up of the best NASA Artemis 2 gear on planet Earth [Space.com]
- Satellite servicing startup Starfish taps Quindar for mission operations software [SpaceNews]
- Will a bright comet adorn our early spring sky? Why astronomers are getting excited about Comet C/2026 A1 (MAPS) [Space.com]
Biotech
- FDA chief Makary takes aim at Hims' compounded Wegovy pill plans [Endpoints News]
- Statins don’t cause most of the side effects on package warnings, study finds [STAT News]
- New HIV Vaccine Scaffold Primes Rare B Cells for Broadly Neutralizing Responses [GEN News]
- Novo's threat to sue Hims over Wegovy pill faces legal hurdle [Endpoints News]
- White House launches TrumpRx [Endpoints News]
- Xenotransplantation: Making Silk Purses from Sow Ears [GEN News]
- Top 10 Public Mass Spectrometry Companies [GEN News]
- Deep Learning Model Developed to Help Predict Functional Impact of Regulatory Mutations [GEN News]
- Samsung and CEPI Partner to Boost Vaccine Manufacturing Preparedness for Future Epidemic, Pandemic Threats [GEN News]
- Veradermics CEO has a great hair day with 122% pop in IPO [Endpoints News]
- #ISC26: Bayer’s asundexian reduced ischemic strokes by 26% in Phase 3 trial [Endpoints News]
- Bristol Myers draws pipeline excitement as several data readouts near [Endpoints News]
- GLP-1s and the Super Bowl [Endpoints News]
- Thermo Fisher, Charles River workforce cuts; WuXi signs contract with Vertex [Endpoints News]
- Telehealth provider Hims goes after Novo's weight loss pill with compounded version [Endpoints News]
- Eikon IPO analysis: Big biotech names, big valuation cut [Endpoints News]
Asia
- Takaichi: the Japanese prime minister America has been waiting for [Asia Times]
- China economic rebalancing to test Koreans before benefiting them [Asia Times]
- Indonesia’s $80 Billion Wake-Up Call [The Diplomat]
- How Japan can function as Taiwan deterrence logistics hub [Asia Times]
- In Kyrgyzstan, US Special Envoy Gor Brushes Aside Visa Restrictions, Promotes Business [The Diplomat]
- Can One Nation Turn Its Polling Hype Into Seats in Parliament? [The Diplomat]
- Japan’s Inbound Tourism Is Booming, But Japanese Are Less Interested in Going Abroad [The Diplomat]
- Bangladesh’s 2026 Election Is a Litmus Test for Global Democratic Revival [The Diplomat]
- China and the US Want Africa’s Critical Minerals. Will African Countries Actually Benefit? [The Diplomat]
- India’s Strategic Autonomy for a Capital Lifeline? [The Diplomat]
- What Yang Sung Ho’s Dismissal Reveals About Kim Jong Un’s New Accountability [The Diplomat]
- India’s R&D crisis isn’t a money problem [Asia Times]
- Pakistan’s Stature Grows as Trump Invites It to Participate in Iran-US Nuclear Talks [The Diplomat]
- Japan-Philippines Security Cooperation in the Indo-Pacific Region [The Diplomat]
- North Korea Waits for Major Concessions From Trump [The Diplomat]
- Envisioning US Forces Korea’s role in a Taiwan war [Asia Times]
- Who Will Succeed Xi Jinping? [The Diplomat]
- Vietnam Planning For ‘Second US Invasion,’ Leaked Government Document Claims [The Diplomat]
- Philippine Congressional Committee Says Marcos Impeachment Efforts Lack Substance [The Diplomat]
- The Powers Shaping Global Conflict From the Shadows [The Diplomat]
Africa
- Kagame to UN: Stop treating Congo like a spoilt child [The East African]
- UK sanctions Sudanese army and paramilitary leaders over ongoing conflict [The East African]
- As South Sudan’s peace pact collapses, mediators try again [The East African]
- In Dubai, Samia seeks to repair Tanzania’s image after chaotic election [The East African]
- Bobi Wine’s case for suspending Uganda from the Commonwealth [The East African]
- EAC merger maze: New approval rules unsettle corporates as Safaricom deal tests the waters [The East African]
South America
- Milei's Argentina inks trade, investment deal with Trump's United States [Buenos Aires Times]
- Argentina signs US trade deal that cuts hundreds of tariffs [Buenos Aires Times]
- Clothes producers slam economy minister's comments condemning domestic prices [Buenos Aires Times]
- Epstein files show link to alleged Argentine drug-trafficker ‘Fred’ Machado [Buenos Aires Times]
- Milei apes Trump with ‘rapid response’ office to counter ‘disinformation’ [Buenos Aires Times]
- Argentines have snapped up US$26 billion since loosening of currency controls [Buenos Aires Times]
- Argentina to set up base camp in Kansas City for 2026 World Cup [Buenos Aires Times]
- US senator asks Bessent to terminate US$20-billion Argentina swap line [Buenos Aires Times]
- Frontrunner in Colombia’s election race barred from united left primary [Colombia Reports]
- Reidel justifies debt clearance amid nuclear plant graft claims [Buenos Aires Times]
- Heirs denounce Milei’s controversial transfer of San Martín’s sabre [Buenos Aires Times]
Australia
- Local helps remove croc outside NT bottle shop during school drop off – video [The Guardian Australia]
UK News
- Resignations, denials and excuses: Epstein fallout hits some harder than others [The Guardian UK]
- The Mandelson Scandal: has Starmer finally lost control? – Politics Weekly [The Guardian UK]
- David Furnish calls alleged phone hacks of him and Elton John ‘an abomination’ [The Guardian UK]
- Is Mandelson scandal the end for Starmer? - The Latest [The Guardian UK]
- UK to cut climate finance to poor countries by a fifth despite promising more help [The Guardian UK]
- Airlines should tell UK customers the carbon impact of flights, watchdog says [The Guardian UK]
- Anger over Scottish salmon farm inspections amid 35m unexpected fish deaths [The Guardian UK]
- Why the Bank of England is holding rates despite a weakening economy | Phillip Inman [The Guardian UK]
- ‘Sorry for having believed Mandelson’s lies’: Keir Starmer apologises to Epstein victims – video [The Guardian UK]
- Why all Olympic curling stones come from a Scottish island [BBC UK]
- What are files from Mandelson’s US ambassador appointment likely to reveal? [The Guardian UK]
Top Journals
- Sharp cutbacks in field tests could threaten quality of 2030 U.S. census [Science]
- Inside the quest to make a safer football helmet [Science]
- Controversial Danish vaccine research group faces new allegations [Science]
- These beetles wear chemical ‘invisibility cloaks’—and will die if they’re removed [Science]
- A hack-proof internet? Quantum encryption could be the key [Science]
- FDA-approved drug may address a major cause of infertility [Science]
- Imagination isn’t just for humans, this famous ape shows [Science]
- A generalizable foundation model for analysis of human brain MRI [Nature Neuroscience]
- Publisher Correction: Diversity and immune dynamics of choroid plexus macrophages are shaped by distinct developmental origins [Nature Neuroscience]
- Global multi-ancestry genome-wide analyses identify genes and biological pathways associated with thyroid cancer and benign thyroid diseases [Nature Genetics]
- Polygenic risk scores in thyroid cancer screening, diagnosis and management [Nature Genetics]
- Unintended risks of sarcopenic obesity during weight-loss interventions in older people [Nature Medicine]
- Correction: Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility [eLife]
- Ly6G+ granulocytes-derived IL-17 limits protective host responses and promotes tuberculosis pathogenesis [eLife]
- A high-resolution, easy-to-build light-sheet microscope for subcellular imaging [eLife]
- ZFT is the major iron and zinc transporter in Toxoplasma gondii [eLife]
- Dorsoventral-mediated Shh induction is required for axolotl limb regeneration [eLife]
- Stochasticity in cancer immunotherapy stems from rare but functionally critical Spark T cells [Cell]
- Symbiotic entrenchment through ecological Catch-22 [Cell]
- Sensory neurons drive immune exclusion by stimulating a dense extracellular matrix in the breast cancer tumor microenvironment [Cell]
Long Reads
- Bunnings’ backyard pods won’t fix the housing crisis, but they signal a shift [The Conversation]
- Inside the Mouth of Earth’s Oldest Bird [Nautilus]
- Why comparisons between AI and human intelligence miss the point [The Conversation]
- The Voice campaign entrenched immature politics. We must do better for First Nations people [The Conversation]
- Publishing tips, poetry and witty takes on classics: 6 of the best Australian literary podcasts [The Conversation]
- If Australia and Indonesia agreed to end new thermal coal mines, it could drive the green transition. [The Conversation]
- TV Review: “Riot Women,” Streaming on BritBox [The New Yorker]
- Dream Engineering Could Help You Solve Problems While You Sleep [Nautilus]
- What exactly is misconduct in public office and could Peter Mandelson be convicted? [The Conversation]
- Why Teflon Is Losing Its Sticking Power [Nautilus]
- Bonus Daily Cartoon: Let It Melt [The New Yorker]
- A Haunting in Brooklyn [Longreads]
- Daily Cartoon: Thursday, February 5th [The New Yorker]
- The Murder of ‘The Washington Post’ [Longreads]
- The Trump Administration Plays the Name Game [The New Yorker]
- Africa’s cultural landmarks: Tsodilo Hills, Botswana [Aeon]
- The Assault on Ukraine’s Power Grid [The New Yorker]
- The People Who Will Actually Make Universal Child Care Happen [The New Yorker]
- How to Break Up with Your Phone [The New Yorker]
- Between being and emptiness [Aeon]
Protein Data Bank
- 3D 10AD: Cryo-EM structure of the human BK channel bound to the agonist NS1619
- 3D 10ID: Membrane-bound, reversed VP5* trimer (rotavirus spike protein)
- 3D 10JU: Crystal Structure of serine/threonine-protein kinase (AEK1) T376D, S395D Mutant from Trypanosoma brucei (AMP-PNP)
- 3D 10KE: Crystal structure of Capsular polysaccharide biosynthesis protein from Bordetella pertussis in complex with NAD and uridine-diphosphate-n-acetylgal...
- 3D 10LG: Crystal structure of Streptococcus thermophilus SHP pheromone receptor Rgg3 in complex with Rgg3bp13
- 3D 21FB: Structure of minor species of Abeta fibrils from AppNL-FPsen1P117L mice
- 3D 21IE: The MIDN Catch-IRF4 (A8S) fusion protein
- 3D 21IK: The MIDN Catch-IRF4 (V2T) fusion protein
- 3D 21IP: The MIDN Catch-IRF4 (A8C) fusion protein
- 3D 22GA: Crystal structure of sorghum sulfotransferase LGS1 reveals sulfation-assisted BC-ring formation in strigolactone biosynthesis
PDB Nitrogen Cycle
- 3D 9CWY: Crystal structure of HLA-A*03:02 in complex with a wild-type PIK3CA peptide
- 3D 9CWZ: Crystal structure of HLA-A*03:02 in complex with a mutant PIK3CA peptide
- 3D 9G7L: Structure of the proline-rich binding domain of Tesup-1 in complex with dZfc3h1 peptide
- 3D 9G83: Respiratory supercomplex CI1-CIII2-CIV2-(cbb3)1 from alphaproteobacterium
- 3D 9G9Y: Respiratory supercomplex CI2-CIII2-CIV2 (megacomplex) from alphaproteobacterium
- 3D 9G9Z: Respiratory supercomplex CI1-CIII2-CIV1 (respirasome) from alphaproteobacterium
- 3D 9GAE: Respiratory supercomplex CI1-CIII2-CIV2 from alphaproteobacterium
- 3D 9I3X: Structure of anti-EV71 human monoclonal antibody 16-2-11B Fab
- 3D 9I4D: Structure of anti-EV71 human monoclonal antibody 17-2-2B Fab
- 3D 9I4W: Structure of carbamoylated recombinant human butyrylcholinesterase by the biscarbamte 5-(1-hydroxy-2-(piperidin-1-yl)ethyl)-1,3-phenylene bis(piper...
PDB Photosynthesis
- 3D 9G83: Respiratory supercomplex CI1-CIII2-CIV2-(cbb3)1 from alphaproteobacterium
- 3D 9G9Y: Respiratory supercomplex CI2-CIII2-CIV2 (megacomplex) from alphaproteobacterium
- 3D 9G9Z: Respiratory supercomplex CI1-CIII2-CIV1 (respirasome) from alphaproteobacterium
- 3D 9GAE: Respiratory supercomplex CI1-CIII2-CIV2 from alphaproteobacterium
- 3D 9H3G: Structure of the Arabidopsis thaliana 80S ribosome in complex with P- and E-site tRNAs and mRNA
- 3D 9H6I: Structure of the Arabidopsis thaliana 80S ribosome in complex with P- and E-site tRNAs, mRNA, and thermospermine
- 3D 9HES: Structure of the Arabidopsis thaliana 80S ribosome OVAC mutant in complex with P- and E-site tRNAs, mRNA, and thermospermine
- 3D 9HMW: Structure of the Arabidopsis thaliana 80S ribosome OVAC mutant in complex with P- and E-site tRNAs and mRNA
- 3D 9I26: inactive Form II Rubisco from Rhodospirillum rubrum
- 3D 9I27: activated Form II Rubisco from Rhodospirillum rubrum with bound Magnesium and CABP
PDB PFAS Degradation
- 3D 9CWY: Crystal structure of HLA-A*03:02 in complex with a wild-type PIK3CA peptide
- 3D 9I3X: Structure of anti-EV71 human monoclonal antibody 16-2-11B Fab
- 3D 9QCH: Complex of Ovine Serum Albumin with Cephalosporin C
- 3D 9RPL: Lactobacillus acidophilus SlpA self assembly domains I-II (aa 49-308)
- 3D 9S42: Complex of Equine Serum Albumin with Hydrolyzed Ampicillin
- 3D 9S43: Complex of Equine Serum Albumin with Oxacillin
- 3D 9S73: Complex of Equine Serum Albumin with Ampicillin
- 3D 9SC5: Complex of Ovine Serum Albumin with Oxacillin
- 3D 9SDJ: Complex of Ovine Serum Albumin with Hydrolyzed Ampicillin
- 3D 9DAY: Crystal Structure of the Transcriptional Regulator HcpR from Porphyromonas Gingivalis
Project Gutenberg
- A Study in Scarlet EPUB PDF
- Persuasion EPUB PDF
- The Time Machine EPUB PDF
- Dubliners EPUB PDF
- The Complete Poetical Works of Percy Bysshe Shelley EPUB PDF
- The Republic EPUB PDF
- Adventures of Huckleberry Finn EPUB PDF
- The Yellow Wallpaper EPUB PDF
- Grimms' Fairy Tales EPUB PDF
- Little Women EPUB PDF
- Les Miserables EPUB PDF
- The Iliad EPUB PDF
- The Souls of Black Folk EPUB PDF
- The Divine Comedy EPUB PDF
- Jane Eyre EPUB PDF
GitHub bioRxiv
-
Zhaojp-Frank/AwesomePaper-for-AI
10
Unknown
Awesome system papers for AI
-
RagnarGrootKoerkamp/sassy
99
Rust
Fast approximate string searching
-
eugenevinitsky/lea
9
TypeScript
bluesky portal for researchers
-
soedinglab/PMGen
21
Python
peptide-MHC modeling, binding prediction, and protein design.
-
rpatrik96/bibtexupdater
61
Python
Tools for managing BibTeX bibliographies: automatically update preprints to publ...
-
bytedance/Protenix
1561
Python
Toward High-Accuracy Open-Source Biomolecular Structure Prediction.
-
mdozmorov/RNA-seq_notes
53
Unknown
A continually expanding collection of RNA-seq tools
-
Hawksight-AI/semantica
657
Python
Semantica🧠: Open-Source Semantic Layer & Knowledge Engineering Framework for bui...
-
sagar87/spatialproteomics
39
Python
Spatialproteomics is a light weight wrapper around xarray with the intention to ...
-
cafferychen777/mLLMCelltype
631
R
Cell type annotation for single-cell RNA-seq using multi-LLM consensus
Synthetic Biology
- Protein-inducible ribosomal frameshifting enables programmable translational control for genetic circuit design in Escherichia coli.
- A validation for sex differences in gut microbiome of essential hypertension based on cohort analysis.
- KDM5B cooperates with CRL4B complex to promote the tumorigenesis of ER+ breast cancer via regulating cholesterol metabolism.
- Nitrogen starvation induces arbuscular mycorrhizal fungi to optimize resource allocation in sugarcane roots via suppression of basal metabolism.
- Limitations of traditional mycotoxin control and biotechnological advances toward sustainable solutions.
- bHLH transcription factors: Key regulators of bioactive component biosynthesis in medicinal plants.
- Characterization of Usher Syndrome Type 2-Associated Proteins in the Retina via Affinity Purification-Mass Spectrometry.
- Combining metabolic engineering and fermentation optimization to achieve cost-effective oil production by Cutaneotrichosporon oleaginosus.
- Preferential use of alkyl-acyl phosphatidylinositol for GPI biosynthesis and diagnostic potential of lipidomics for inherited GPI deficiencies.
- Compartmentalized branched-chain amino acid metabolism orchestrates colorectal cancer dissemination via an UMP-vimentin axis.
- Refactoring two-component systems for tunable gene expression regulation and upgraded bacterial sensing.
- Rewriting endogenous human transcripts with dual CRISPR-guided 3' trans-splicing.
- L-phenylalanine induces cutin and wax biosynthesis in muskmelon fruit epidermis via fatty acid and triterpenoid pathways.
- Molecular mechanism of SmERF B3-4 in regulating lignin biosynthesis by modulating Sm4CL11 in Salix matsudana.
- Nitrogen enhances cadmium phytoremediation in poplar via physiological, molecular, and rhizobacterial mechanisms.
Biotechnology
- AAV NRF2 Gene Therapy Preserves Retinal Structure and Function in Rodent Models of Oxidative Damage.
- PTPN2 deficiency amplifies inflammatory signalling and impairs functional maturation of human stem cell-derived islets.
- Ex vivo long-term expansion of human hematopoietic stem and progenitor cells as a tool for modeling vector integration sites and clonality.
- Current Advances and Applications of Retinal Organoids.
- A combinatorial synthetic strategy for developing genome-editing protein-delivery agents targeting mouse retina.
- Sporoplasm: The initial cell in microsporidia life cycle.
- Limitations of traditional mycotoxin control and biotechnological advances toward sustainable solutions.
- Field-deployable CRISPR-Cas variants for rapid on-site detection of plant pathogens.
- CRISPR/Cas9-Engineered Salmonella Phage Displaying Antimicrobial Peptide LL37 for Enhanced Antibacterial Activity.
- Rewriting endogenous human transcripts with dual CRISPR-guided 3' trans-splicing.
- CRISPR-initiated exponential amplification on fluorescently-barcoded microspheres for deep learning-assisted multiplexed HPV detection.
- Highly efficient gene editing via targeted Cas9 insertion into chicken housekeeping gene.
- Dual knockout of Fas and TCRα in Jurkat reporter cells enables highly sensitive identification of antigen-specific TCRs.
- CRISPR/Cas9-mediated SiZAT12 mutagenesis enhances drought tolerance without yield penalty in foxtail millet (Setaria italica).
- CRISPR mediated inactivation of OsPLDβ1 phospholipase enhances drought tolerance by upregulating stress-related genes and antioxidant enzymes in rice.
AI & Machine Learning
- Integrative cross-tissue and spatially resolved single-cell profiling uncovers tumour-educated inflammatory remodelling of tissue-resident macrophage ecosystem with immunotherapeutic prognostic significance in pan-cancer.
- Advances in the postoperative care of the liver transplant recipient.
- Exploring the Ethical Dimensions of AI-Driven Patient Monitoring in Critical Care Nursing: A Systematic Review.
- Spectral Representation of Neurochemicals With Phase, Frequency Offset, and Lineshape Invariance: Application to JPRESS for In Vivo Concentration and T(2) Mapping by Deep Learning.
- Introducing AutoML framework for Drug-Drug Interaction Prediction: Application of AutoGluon.
- Identification of immune-related genes and serum miR-100-5p in idiopathic inflammatory myopathy-related heart failure by integrated bioinformatics analysis and clinical validation.
- Artificial intelligence in emergency surgery: a scoping review within the artificial intelligence in emergency and trauma surgery (ARIES) project.
- TFAP2A transcriptionally regulates B3GALT2 to affect gouty arthritis progression through pyroptosis: a study based on machine learning and multi-omics integration analysis.
- Artificial intelligence in medical ethics education: a descriptive study of eight models in multiple choice question generation.
- Performance of machine learning algorithms in diffusion tensor imaging of movement disorders: an exploratory meta-analysis.
- AMP-CapsNet: a multi-view feature fusion approach for antimicrobial peptide prediction using capsule networks.
- Explainable machine learning for depression risk prediction in adults with obesity: development of an online tool.
- AI-driven biomarker learning for the early diagnosis of neurodegenerative diseases: ABLEDx.
- AI-driven 3D virtual surgical planning in total hip arthroplasty: a machine learning approach for precision implant positioning and improved clinical outcomes.
- Ethical concerns and strategies for implementing artificial intelligence in healthcare: a review of empirical studies.
Neuroscience
- Time-weighted lactate and glucose-lactate ratio outperform static values in ICU mortality prediction after traumatic brain injury: a retrospective cohort study.
- Clinical outcomes of short-segment cement-augmented pedicle screw fixation combined with vertebroplasty in patients with stage III Kummell's disease.
- Bridging the blood-brain barrier: strategies to improve delivery of biologics to tumors in the brain.
- Magnesium silicate nanosheets enable sustained hydrogen release to attenuate secondary brain injury following intracerebral hemorrhage.
- Exercise-derived exosomes: molecular mediators of systemic health and disease therapy.
- AI-driven biomarker learning for the early diagnosis of neurodegenerative diseases: ABLEDx.
- Risk factors for neonatal brain injury in neonates born to mothers with preeclampsia: a retrospective study.
- DefaceQA - automated quality assessment of brain MRI defacing software.
- A 3D gut-brain-vascular platform for bidirectional crosstalk in gut-neuropathogenesis.
- Target-Specificity and repeatability in neuro-cardiac-guided TMS for heart-brain coupling.
- Corrigendum to Simple quantitative planimetric measurement of nigrosome-1 for clinical settings [Journal of the Neurological Sciences 454 (2023) 120857].
- Corrigendum to "From ancient fears to airborne threats: fMRI insights into neural fear responses" [Brain Cogn. 191 (2025) 106371].
- Understanding the Older Brain in Depression.
- Beta-Caryophyllene Restores Liver-Brain Axis Integrity in Thioacetamide-Induced Hepatic Encephalopathy: Behavioral and Molecular Insights.
- Dexamethasone as an Adjuvant to Erector Spinae Plane Block Is Associated With Improved Neuromonitoring Parameters and Analgesia in Pediatric Spine Surgery.
Climate Science
- To ABG or Not to ABG-Reducing Inappropriate Arterial Blood Gas Testing in Critical Care.
- Climate change drives convergent evolution of root traits on Sky Island climate relicts.
- Climate change and pesticide resistance: A synthesis on emerging mechanisms and evolutionary dynamics.
- Insect declines: Challenges and solutions.
- Sustainable application of waste residue from coal gasification process in low-carbon cement: multiscale evaluation, hydration behavior, mechanical performance, and environmental assessment.
- Closing the loop: A systematic review of artificial intelligence in circular e-waste management.
- A promising biotic ligand model for predicting the phytotoxicity of hexavalent chromium (Cr(VI)) during seawater intrusion: Roles of sulfate, chloride, and Cr(VI) species.
- Advances in carbon capture, conversion, and utilization: A review of sustainable chemical production pathways.
- Electron beam-induced decomposition of nitrous oxide (N(2)O) and the critical role of oxygen.
- Physiology and behaviour of eastern oysters (Crassostrea virginica) and soft-shell clams (Mya arenaria) under hypoxic and heatwave conditions.
- Deeper waters, more calcifiers: Spatial variation in benthic assemblages highlight conservation challenges in sub-Antarctic Marine Protected areas.
- Green and red nets showed opposite influence on carotenoid accumulation in citrus by differential regulation of CitPSY and CitCCD4 gene expression.
- CRISPR mediated inactivation of OsPLDβ1 phospholipase enhances drought tolerance by upregulating stress-related genes and antioxidant enzymes in rice.
- Combined "omics" and physiological approaches highlight the roles of the GABA shunt and mitochondria-related functions in rice seed longevity.
- Life Cycle Assessment of road expansion: Baseline environmental impacts in El Salvador.
Medicine
- Integrative cross-tissue and spatially resolved single-cell profiling uncovers tumour-educated inflammatory remodelling of tissue-resident macrophage ecosystem with immunotherapeutic prognostic significance in pan-cancer.
- ALKBH5 Orchestrates Ferroptosis-Driven Tumor Suppression: An LLM-Powered Discovery in Prostate Cancer.
- Mapping the clinical landscape of multifunctional CAR T cells: targets, trends, and synergies.
- Acute Graft-Versus-Host Disease After Deceased-Donor Liver Transplantation: A Case Report.
- Therapeutic Efficacy of Oral Tofacitinib in Pediatric Prurigo Nodularis: A Case Series With a Review of Literature.
- Janus Kinase Inhibitors as a Therapeutic Option for Chronic Spontaneous Urticaria Refractory to Antihistamines and Omalizumab: A Case Series.
- Methods and Instruments to Measure ICU Healthcare Professionals' Workload Related to Medical Technology-Protocol for a Scoping Review.
- VPS4A activates glycolytic metabolism via MYO1C to promote radioresistance in ESCC.
- The utility of urine lipoarabinomannan as a tuberculosis treatment monitoring tool in people living with HIV.
- Time-weighted lactate and glucose-lactate ratio outperform static values in ICU mortality prediction after traumatic brain injury: a retrospective cohort study.
- CI-994 is a dual modulator of class I HDACs and Wnt/β-catenin signaling for the treatment of Alzheimer's disease.
- In vitro assays for investigating the immunomodulatory properties of human mesenchymal stromal cells.
- Refining the PTV margin determination for VMAT SBRT lung treatment through moving target dose model to account for respiratory motion uncertainty.
- A biohybrid platform integrating bacterial propulsion and photoresponsive nanomedicine for adequate intratumoral drug delivery.
- The minimally invasive approach for lateral malleolus fractures plating demonstrating less pain, shorter operative time and earlier discharge compared to open approach: a prospective randomized controlled trial.
Genomics
- Integrative cross-tissue and spatially resolved single-cell profiling uncovers tumour-educated inflammatory remodelling of tissue-resident macrophage ecosystem with immunotherapeutic prognostic significance in pan-cancer.
- Outbreak investigation and genomic analysis reveal hidden transmission networks of KPC-2-producing Enterobacterales in a South Korean hospital.
- RT-ICI therapy induces a distal immunometabolic axis that shapes systemic macrophage polarization and enhances local T cell immunity.
- Genetic affinities between the ancient Greek colony of Amvrakia and its metropolis.
- Antimicrobial resistance and virulence of Enterococcus faecium isolates from a traditionally fermented dairy beverage from Uganda.
- Developmental neurotoxicity of thyroid hormone system-disrupting chemicals: a systems-level exploration using multi-omics approach.
- The use of new approach methodologies (high-throughput transcriptomics) to study nanoagrochemicals: mechanisms of toxicity of a commercial copper oxychloride to soil model invertebrates (Enchytraeus crypticus).
- Estrogen receptor β target gene expression reveals novel repressive functions in aggressive breast cancer.
- Modeling and application of alzheimer's disease complex trait prediction based on multi-task learning.
- Quorum-quenching lactonase AiiO from Ochrobactrum quorumnocens B44 isolated from bark compost attenuates the virulence of plant pathogens.
- Inositol Hexaphosphate and Inositol Prevent WD/CCl₄-Induced Metabolic Dysfunction-Associated Steatohepatitis in Mice.
- Isolation, characterization and dairy application of a novel bacteriophage fBSPA4 against Salmonella enterica.
- Serum procalcitonin: A novel tumor biomarker for diagnosis and disease monitoring in fibrolamellar hepatocellular carcinoma.
- ROS-Driven Rewiring of Hippo-Inflammation-Polycomb Axis by PFOA in 2D and 3D Lung Epithelial Models.
- GenomeSyn-II: a comparative genomics framework integrating synteny visualization.
Immunology
- Galectin-3 in the Lateral Ventricle Regulates Immune Functions.
- LpqH-tagged microvesicles as mRNA vaccine carriers for specific delivery of mRNA into macrophages.
- From Amphiphiles to mRNA platforms: emerging vaccination strategies for pancreatic cancer.
- Sex differences in disease severity and immune responses in murine and human inflammatory arthritis.
- Computational design of a novel multi-epitope vaccine candidate against group A rotavirus.
- AMP-CapsNet: a multi-view feature fusion approach for antimicrobial peptide prediction using capsule networks.
- Association between COVID-related health literacy and vaccine acceptance: results of a nationwide cross-sectional study in Hungary.
- Prevalence of herpes zoster in individuals who have received COVID-19 vaccine and/or had COVID-19: a cross-sectional study.
- Forecasting and quantifying the role of vaccination strategies in the 2025 Texas measles outbreak: a modeling and time series analysis approach.
- Randomized pilot study of camrelizumab with or without autologous cytokine-induced killer cells in refractory clear cell renal cell carcinoma.
- Balancing innovation and accessibility in infection imaging: lessons from the [(99m)Tc]Tc-besilesomab paradox.
- Cellular immune response following homologous and heterologous BNT162b2 booster vaccination after primary immunization with BNT162b2 and CoronaVac respectively.
- Phase I Study Evaluating a Monoclonal Fc-Silenced SARS-CoV-2 Antibody in Patients With Moderate-to-Severe COVID-19.
- Contextualizing the Development of Anti-HER2 Therapies for Patients with Advanced Urothelial Carcinoma.
- Two vaccine-associated measles cases: Transmission or coincidental cases?
Microbiology
- Galectin-3 in the Lateral Ventricle Regulates Immune Functions.
- Plant diversity induces shifts from microbial generalists to specialist by enhancing niche differentiation, microbiome connectivity, and network stability in a temperate grassland.
- Species-level dynamics of gastric microbiome after Helicobacter pylori eradication in high-risk Mongolian population.
- Temporal and spatial shifts in the foliar fungal endophyte community of Norway spruce (Picea abies) over 150 years in Finland.
- Quantifying lifetime risk for 1,401 infectious diseases across the diabetes spectrum using a Bayesian approach.
- First report of Candidozyma auris in Vietnam.
- Characteristics comparative of gut microbiota in four small mammal species co-occurring in the Hengduan Mountains: differences in environmental adaptation strategies between alien and endemic species.
- A validation for sex differences in gut microbiome of essential hypertension based on cohort analysis.
- Low-inflammatory response phenotypes in elderly urinary tract infections: pathogen type, antimicrobial resistance, and comorbidity-associated risk profiles.
- An aptamer-based "Gate-lock-key" strategy for metal-organic framework nanozyme-catalyzed colorimetric detection of multidrug-resistant bacteria.
- Point-of-use colorimetric detection of Escherichia coli in food matrices with DNAzyme crosslinked hydrogels.
- Enhanced resistance and resilience of anaerobic digestion microbiome after single and dual short-term disturbances.
- Microbiome by transcriptome interactions triggered by a switch to an alternative diet in Nellore cattle.
- Quorum-quenching lactonase AiiO from Ochrobactrum quorumnocens B44 isolated from bark compost attenuates the virulence of plant pathogens.
- Management of infections caused by Gram-negative bacteria in severely immunocompromised hosts employing Outpatient Parenteral Antimicrobial Therapy (OPAT): Preliminary evidence from a real-world observational study.
Evolutionary Biology
- Vertebrate-wide transcriptomic screening identifies immune cell-specific expression of the conserved OR-κ gene.
- A reference-free pipeline for detecting shared transposable elements from pan-genomes to retrace their dynamics in a species.
- Organellar genome evolution in Camellia tianeensis (Theaceae): comparative insights into RNA editing, codon usage, and DNA transfer between chloroplast and mitochondrion.
- Spatio-temporal evolution and driving factors of China's foreign aid: a country-level analysis.
- Climate change drives convergent evolution of root traits on Sky Island climate relicts.
- High-performance temperature regulation of nonlinear CSTRs via a hybrid stellar oscillation optimizer and differential evolution-based PID-F control.
- Convergent extreme reductive evolution in ancient planthopper symbioses.
- Ancient gene flow shapes phylogenetic discordance in a genus of wood-warblers (Aves: Parulidae: Leiothlypis).
- Out of North Africa: Evolution and biogeography of Afro-Arabian dwarf tarantulas (Theraphosidae, Ischnocolinae).
- Evolution of Pre-Genetic Semantic Information in Protocells Under Variable Inheritance Fidelity.
- Regulating hydrogen-bond network via a low-viscosity electrolyte for hydrogen evolution reaction-free aqueous sodium-ion batteries.
- Highly selective photocatalytic conversion of CO(2) to hydrocarbons, H(2) evolution, and photodegradation of CV dye using SbSI and SbSeI as catalysts.
- RSM-optimized Mg/Al-LDH biochar composite for enhanced phosphorus removal: Insights into interlayer structure evolution and adsorption mechanism.
- Research note: Molecular characteristics and genetic evolution of H1N1 avian influenza virus from wild birds in Shanghai, China.
- Deterministic Evolution of Aptamers via a Microfluidic-Integrated Robotic Platform Using Complex Exosomes as Targets.
Molecular Ecology
- Plant diversity induces shifts from microbial generalists to specialist by enhancing niche differentiation, microbiome connectivity, and network stability in a temperate grassland.
- Systematic revision of Paralongidorus (Nematoda: Longidoridae) based on molecular and morphological evidence, with the description of a new species from Spain.
- Drivers of Scarabaeidae (Coleoptera) attraction: the roles of habitat diversity and bait type evaluated through EUNIS habitat classes.
- Wild edible plants and associated indigenous knowledge among the Setswana-speaking people of North West Province in South Africa.
- First record of Penicilliopsis clavariiformis Solms. on seeds of Diospyros ferrea (Willd.) Bakh. from the Northern Western Ghats, India.
- Corrigendum to "Biodiversity-dependent invasiveness of naive river epilithic biofilms by anthropogenic antibiotic resistance at the interface between the human, animal and environmental spheres" [Sci. Total Environ. Volume 1012 (2026) 181237].
- Diversity and pathogen surveillance in chigger mites across Brazil's five biogeographic regions.
- Insect declines: Challenges and solutions.
- Hydrological period conversions induce micro-eukaryotic community homogenization along the eastern route of China's South-to-North Water Diversion Project.
- Effects of mycorrhizal dominance on species diversity and carbon stock in a large temperate forest region.
- Enhancing the effectiveness of behavioral intervention through high-performing media and the RE-AIM framework: Randomized field experiments on reducing unintentional propagule introduction.
- A preliminary study and assessment of the effects of beaver engineering on river condition and its relevance for biodiversity net gain.
- Deeper waters, more calcifiers: Spatial variation in benthic assemblages highlight conservation challenges in sub-Antarctic Marine Protected areas.
- Rainfall alters network structure, while fragmentation results in the breakdown of a mixed-species group of birds.
- Unlocking the potential of other effective area-based conservation measures (OECMs) for achieving conservation targets: A global scoping review.
arXiv Physics
- PDF Explosive eruption cycles in a rotating Z-pinch
- PDF Modeling integrated frequency shifters and beam splitters
- PDF Westcott $g$ Factors Extended to Arbitrary Neutron Energy Spectra
- PDF Quantum noise scaling in continuously operating multiparameter sensors
- PDF Efficient net-gain integrated optical parametric amplifier in the quantum regime
- PDF Extended Rydberg Lifetimes in a Cryogenic Atom Array
- PDF Poisson Log-Normal Process for Count Data Prediction
- PDF Photonic neuromorphic processing with coupled spiking silicon microrings
- PDF The Effects of Non-ideal Mixing in Planetary Magma Oceans and Atmospheres
- PDF Higher-order adaptive behaviors outperform pairwise strategies in mitigating contagion dynamics
- PDF Active Soft-Impact Oscillator: Dynamics of a Walking Droplet in a Non-Smooth Potential
- PDF Self-Portrait of the Focusing Process in Speckle: III. Tailoring Complex Spatio-Temporal Focusing Laws To Overcome Reverberations in Reflection Imaging
- PDF Self-Portrait of the Focusing Process in Speckle: I. Spatio-Temporal Imaging of Wave Packets in Complex Media
- PDF On particle dynamics in steady axial rotor flows
- PDF An FWCI decomposition of Science Foundation Ireland funding
arXiv Mathematics
- PDF Diffusion Model's Generalization Can Be Characterized by Inductive Biases toward a Data-Dependent Ridge Manifold
- PDF Towards uncertainty quantification of a model for cancer-on-chip experiments
- PDF Convex unions and completions from simplicial pseudomanifolds
- PDF Optimism Stabilizes Thompson Sampling for Adaptive Inference
- PDF Excursion decomposition of the XOR-Ising model
- PDF Vector-Valued Singular Integrals on Locally Doubling Spaces
- PDF Computing Diffusion Geometry
- PDF Lattices from Pointed Building Sets: Generalized Ornamentation Lattices
- PDF Categories graded by group homomorphisms
- PDF Finite time singularities in the Landau equation with very hard potentials
- PDF The Signed Wasserstein Barycenter Problem
- PDF Normalization of ReLU Dual for Cut Generation in Stochastic Mixed-Integer Programs
- PDF Inverse Depth Scaling From Most Layers Being Similar
- PDF Stability of the $L^{p}$-Poincaré inequality for the Lebesgue and Gaussian probability measures with explicit geometric dependency
- PDF Global solvability and stabilization in multi-dimensional small-strain nonlinear thermoviscoelasticity
arXiv Computer Science
- PDF Shared LoRA Subspaces for almost Strict Continual Learning
- PDF Pseudo-Invertible Neural Networks
- PDF Predicting Camera Pose from Perspective Descriptions for Spatial Reasoning
- PDF DyTopo: Dynamic Topology Routing for Multi-Agent Reasoning via Semantic Matching
- PDF SwimBird: Eliciting Switchable Reasoning Mode in Hybrid Autoregressive MLLMs
- PDF CommCP: Efficient Multi-Agent Coordination via LLM-Based Communication with Conformal Prediction
- PDF Thinking with Geometry: Active Geometry Integration for Spatial Reasoning
- PDF DFlash: Block Diffusion for Flash Speculative Decoding
- PDF InterPrior: Scaling Generative Control for Physics-Based Human-Object Interactions
- PDF V-Retrver: Evidence-Driven Agentic Reasoning for Universal Multimodal Retrieval
- PDF Can vision language models learn intuitive physics from interaction?
- PDF Splat and Distill: Augmenting Teachers with Feed-Forward 3D Reconstruction For 3D-Aware Distillation
- PDF PhysicsAgentABM: Physics-Guided Generative Agent-Based Modeling
- PDF AP-OOD: Attention Pooling for Out-of-Distribution Detection
- PDF Curiosity is Knowledge: Self-Consistent Learning and No-Regret Optimization with Active Inference
arXiv Quantitative Biology
- PDF Mechanisms of AI Protein Folding in ESMFold
- PDF Characterizing Human Semantic Navigation in Concept Production as Trajectories in Embedding Space
- PDF Intermittent precipitation and spatial Allee effects drive irregular vegetation patterns in semiarid ecosystems
- PDF Somatic Mechanotherapy Activates a Spatiotemporally Synchronized CPTC Wnt Axis for Gut Regeneration
- PDF Specieslike clusters based on identical ancestor points
- PDF Learning virulence-transmission relationships using causal inference
- PDF Combination therapy for colorectal cancer with anti-PD-L1 and cancer vaccine: A multiscale mathematical model of tumor-immune interactions
- PDF Optimal Harvesting in Stream Networks: Maximizing Biomass and Yield
- PDF A novel scalable high performance diffusion solver for multiscale cell simulations
- PDF Protein Autoregressive Modeling via Multiscale Structure Generation
- PDF Uncertainty in Island-based Ecosystem Services and Climate Change
- PDF BrainVista: Modeling Naturalistic Brain Dynamics as Multimodal Next-Token Prediction
- PDF Discovering Mechanistic Models of Neural Activity: System Identification in an in Silico Zebrafish
- PDF The impact of heterogeneity on the co-evolution of cooperation and epidemic spreading in complex networks
- PDF How seed banks evolve in plants: a stochastic dynamical system subject to a strong drift
arXiv Quantitative Finance
- PDF Universal approximation with signatures of non-geometric rough paths
- PDF On the Skew Stickiness Ratio
- PDF Optimal Risk-Sharing Rules in Network-based Decentralized Insurance
- PDF Music as an Asset Class
- PDF Fair Pricing in Long-Term Insurance: A Unified Framework
- PDF Sampled-Data Wasserstein Distributionally Robust Control of Multiplicative Systems: A Convex Relaxation with Performance Guarantees
- PDF DiffLOB: Diffusion Models for Counterfactual Generation in Limit Order Books
- PDF Quantum Speedups for Derivative Pricing Beyond Black-Scholes
- PDF Taming Tail Risk in Financial Markets: Conformal Risk Control for Nonstationary Portfolio VaR
- PDF Soft-Radial Projection for Constrained End-to-End Learning
- PDF A Novel approach to portfolio construction
- PDF Dual Attainment in Multi-Period Multi-Asset Martingale Optimal Transport and Its Computation
- PDF Habit Formation, Labor Supply, and the Dynamics of Retirement and Annuitization
- PDF Reliable Real-Time Value at Risk Estimation via Quantile Regression Forest with Conformal Calibration
- PDF The Innovation Tax: Generative AI Adoption, Productivity Paradox, and Systemic Risk in the U.S. Banking Sector